Acclaim is given to two Australian scientists, Walter and Eliza Hall, who have changed ideas about the memory of the immune system. B cells make antibodies to fight infection. These cells do not die after doing their job and this is not the normal run of things.
A pro-survival proteins is responsible for the cells' continuing existence. It has been proven that the Mcl-1 protein does this, not the Bcl-xL protein as was accepted in the past. Earlier this year tests blocked the activity of Bcl-xL which showed that Mcl-1 stopped apoptosis - death.
Cancer cells survive due to Mcl-1, so there are new possibilities for cancer research. It could also have repercussion for future treatment of the resistance response in organ transplant patients.
A pro-survival proteins is responsible for the cells' continuing existence. It has been proven that the Mcl-1 protein does this, not the Bcl-xL protein as was accepted in the past. Earlier this year tests blocked the activity of Bcl-xL which showed that Mcl-1 stopped apoptosis - death.
Cancer cells survive due to Mcl-1, so there are new possibilities for cancer research. It could also have repercussion for future treatment of the resistance response in organ transplant patients.
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